🍍 $4mil will fund MDMA trials for PTSD; marked ‘Breakthrough Therapy’ by FDA. Pineapple Fund is matching MAPS donations 1:1. Reddit, let’s make history by crowdfunding an incredible treatment for PTSD, in bitcoin!

Hi /r/Bitcoin!

You might've heard of PTSD. It's a debilitating illness usually affecting people who are already victims, like sexual assault survivors who still suffer and are tormented every day since. Not only do they experience traumatic flashbacks, even sleep is no relief thanks to serious nightmares. It is life threatening.

Existing treatment for PTSD aren't great. Therapy can be helpful, but they're often not enough, especially for severe PTSD. There are only two drugs approved by the FDA: SSRIs like Zoloft and Paxil. Those drugs must be taken continuously, and can cause serious side effects. Mania, seizures, inability to orgasm, and suicide are known side effects.

In 1986, a nonprofit named MAPS was started to develop legal contexts for beneficial uses of psychedelics and marijuana. 31 years later, MAPS has found its most promising candidate yet: MDMA-assisted psychotherapy as a treatment for PTSD.

The numbers: 68% (MDMA) versus 25% (placebo)

They've already conducted Phase 2 studies in the US, Canada, Israel, and Switzerland. After a comprehensive therapeutic process involving preparatory sessions, MDMA-assisted therapy sessions, and non-drug therapy sessions, 61% no longer met the criteria for PTSD. This improved to 68% after a year. Of those who met the criteria, many experienced significant reductions in symptoms. This is compared to only 25% for the placebo group, who received all the therapy, but with a sugar pill instead of MDMA.

For most people, the benefits are lasting. MAPS conducted one long-term outcome study, evaluating patients ~3.5 years after the last MDMA-assisted sessions. Average benefits even increased slightly over time.

"The MDMA sessions were the first time I'd ever felt love for myself. It was the first time I'd ever felt happy. I hugged my therapist and said 'Thank you.'"

After MAPS' studies, the FDA granted 'Breakthrough Therapy Designation' to MDMA-assisted psychotherapy.

Now they need to conduct Phase 3 trials, which are far costlier due to requirements for an increased sample size, groups, etc, even through the stage with highest failure rates (Phase 2) is already over. MAPS has achieved the extra-ordinary journey of bringing MDMA-assisted psychotherapy all the way to Phase 3; a drug that pharmas will never touch because it will disrupt their recurring revenue streams of SSRIs.

Phase 3

Phase 3 will cost about $ 25 million. They've raised $ 17 million already ($ 1 mil from PF included), and need another $ 8 million to get to the finish line.

I have never donated to MAPS (or even heard of them) before starting the Pineapple Fund. PF donated $ 1 million, and that inspired another anonymous donator to give another $ 1 million in bitcoin. To whoever you are, you're amazing, and you are inspiring. <3

I believe we, the cryptocurrency community, can fully fund Phase 3 trials. Prescription MDMA could be a gift to this world from the bitcoin community.

If the trial succeeds, it could be approved as early as 2021. MAPS has created a public benefit corporation, fully owned by the non-profit, that would sell MDMA post-approval. This is a scalable and financially sustainable structure that could kickstart a renaissance in research into the therapeutic applications of many different psychedelics.

Pineapple Fund will double the value of every donation to MAPS from today until March 10th, up to $ 4 million.

You can donate with bitcoin. It's like donating bitcoin for $ 30,000 each!

http://www.maps.org/donate-redirect/cryptocurrency

https://blockchain.info/address/1MnCMV9DyVdDZWMfjymbLDKv48UKhoXHEz

You can also donate with legacy payment systems like credit cards or PayPal, and PF will also match that donation.

Your donations are tax deductible (if you're a US taxpayer), and you don't even have to pay capital gains tax. Ask for a receipt if so.

Let's make MDMA medicine a reality, and give the gift of an enjoyable life to those suffering from PTSD. If you believe that psychedelic drugs can have incredible therapeutic potential, then I believe this is one of the highest impact projects today.

And let's do it with cryptocurrency 🙂

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Bitcoin – The Currency of the Internet

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MAPS Receives $1,000,000 in Bitcoin from the Pineapple Fund

On December 14, 2017, the Pineapple Fund, set up by an anonymous cryptocurrency philanthropist, donated 59.89 Bitcoin (BTC), with a value of $ 1,000,000, to the non-profit Multidisciplinary Association for Psychedelic Studies (MAPS), as part of a plan to give away over $ 86 million in BTC to charities and causes around the world.

The Pineapple Fund's gift will directly fund MAPS' upcoming Phase 3 clinical trials of MDMA-assisted psychotherapy for posttraumatic stress disorder (PTSD).

The cryptocurrency community has rallied behind MAPS' work, having donated over $ 120,800 in Bitcoin, Ethereum, and Litecoin since 2013, plus the new support from the Pineapple Fund. These gifts have significantly contributed to MAPS' international psychedelic research, public education, psychedelic harm reduction, and advocacy projects.

We are beyond thankful and inspired by /u/PineappleFund for accepting our donation request. We would also like to extend our gratitude to /r/Bitcoin community members who supported MAPS in the initial thread, including /u/Pixaritdidnthappen, /u/beast-freak, /u/BakingTheCookiesRigh, /u/VerucaNaCltybish, /u/Aaron_FF, /u/joekki, /u/SolidCake, /u/volcanoesarecool, /u/shaggytits, /u/ibrokemywatch, /u/ANinjaOkraSlob, /u/Ou812icRuok, /u/dhxdhxdhx, /u/aorshahar, and /u/nw2shrms.

"The Pineapple Fund's outstanding generosity exemplifies how the growth of cryptocurrency can be leveraged for profound social change," says MAPS Founder and Executive Director Rick Doblin, Ph.D. "The blockchain community is helping to lead the way, not only in decentralized technologies and currencies, but in giving the gift of MDMA-assisted psychotherapy to the world in order to heal trauma and bring greater compassion to psychiatry and medicine."

As a non-profit with no government funding for psychedelic research, MAPS relies on contributions from individuals, businesses, and foundations to make psychedelic therapy a legal treatment. MAPS estimates that Phase 3 clinical trials will cost $ 26 million. With $ 17.3 million already raised or pledged, MAPS still needs $ 8.7 million to make MDMA-assisted psychotherapy legally available to millions of people suffering with PTSD.

MAPS was an early supporter of cryptocurrency donations, and we began accepting Bitcoin donations in December 2013. Currently, MAPS is able to accept cryptocurrency donations in Bitcoin, Ethereum, and Litecoin.

The steep growth in the cryptocurrency market has created a promising new source of support for non-profit psychedelic research, having grown almost 50,000% since 2013 to over $ 500 billion in December 2017, a larger market capitalization than Berkshire Hathaway and Amazon.

In August, the U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy Designation to MDMA-assisted psychotherapy for PTSD, acknowledging that it "may demonstrate substantial improvement over existing therapies" and agreeing to expedite its development and review. If the trials show positive results, FDA approval for MDMA-assisted psychotherapy for PTSD is expected by 2021.

Founded in 1986, MAPS is a 501(c)(3) non-profit research and educational organization that develops medical, legal, and cultural contexts for people to benefit from the careful uses of psychedelics and marijuana. Since its founding, MAPS has raised over $ 45.5 million for psychedelic therapy and medical marijuana research and education. For more information, visit maps.org.

MAPS-sponsored clinical trials are conducted by the MAPS Public Benefit Corporation (MPBC), a wholly owned subsidiary of MAPS formed in 2015 for the special purpose of balancing social benefits with income from legal sales of MDMA, other psychedelics, and marijuana. For more information, visit mapsbcorp.com.

Thank you!

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Bitcoin – The Currency of the Internet